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Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Middle Region) Peptide

CPT1A Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN975267

Aperçu rapide pour Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Middle Region) Peptide (ABIN975267)

Antigène

CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Origine

Humain

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein Region

    Middle Region

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-CPT1A antibody (Catalog #: ARP44796_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

    Sujet

    The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CPT1, CPT1-L, L-CPT1

    Protein Interaction Partner: BCL2

    Protein Size: 756

    Poids moléculaire

    86 kDa

    ID gène

    1374

    NCBI Accession

    NM_001031847, NP_001027017

    UniProt

    P50416
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